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Gene Finding May Help Treating Diabetes

Gene Finding May Help Treating Diabetes

University of Central Florida research team has recently discovered a new gene that controls development of the fat cells. This gene finding may help treating diabetes and obesity.

The team was directed by Pappachan Kolattukudy, the director of University of Central Florida's Burnett School of Biomedical Sciences. They found that a gene named MCPIP controls the fat cells and blood-vessels formation which feeds growing fat tissues.

This new gene finding may help treating diabetes especially type 2 diabetes as well as obesity.

According to Pappachan Kolattukudy, a medicine that shut down functioning can stop obesity as well as the inflammatory diseases such as cardiovascular diseases and diabetes, derived from obesity.

As yet, a protein called PPAR gamma has been widely accepted as the key controller of fat-cells formation in belly along with other important parts of body.

This gene discovery provides the scientists with a new way to develop medicines that may help over 300 million obese people throughout the world. As of 2006, Florida was the 34th among the U.S. states for its obese adult population. Rate of adult obesity in Florida was roughly 30%.

The new gene findings that would be published in the October'09 edition of Journal for Biological Chemistry are presently available on the official website of the journal. The findings have excited the medical professionals especially who are working on obesity and derived diseases.

Dr. Steven Smith, a globally known obesity and diabetes researcher as well as the newly appointed director of Florida Hospital-Burnham Clinical Research Institute said that it's a big thing. PPAR gamma gene is at the hub of everybody's radar to see how the fat cell forms and develops. This will help to develop new medicine for type 2 diabetes.

As of now, the most popular approach for treating the type 2 diabetes is the drugs that help the body producing more insulin, or simple insulin injection. According to Dr. Smith, development of a new drug that helps preventing obesity as well as type 2 diabetes will be revolutionary.

In 2006, a team led by Kolattukudy identified MCPIP gene as the key contributor to the cardiac diseases also discovered its functions as an introducer of fat by emphasizing on its inflammatory influences.

Recent studies has revealed that this increased inflammation of the fat cell induce them to become less responsive to the insulin that potentially triggers type 2 diabetes. Prevalence of fat tissues contribute to inability to processing insulin, which subsequently enables sugars or glucose to flow straight into the blood rather than going into the cells.

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